Eiira Premium

9990 kr

A genetic test for hereditary cancer prevention Simple genetic test done at home Detect hereditary risks for the 10 most common cancers Take preventive action Detect risks for rare hereditary cancers Information that covers 100% of your genome Lifetime updates on what future science can offer for health prevention. One year of free updates

This is for you if:
You are concerned about your cancer risks, including rare cancer risks
You want to benefit fully from current and future discoveries about your genes
You want to learn about your genetic predispositions
You wish to know your DNA to stay healthy
You wish to take full advantage of genome science discoveries to stay healthy

Pay now

9990 kr

Best value

6 Payments

1758 kr/month

10548 kr total

12 Payments

921 kr/month

11043 kr total

Set-up fee SEK 0, administrative fee SEK 0/month, fixed annual interest rate 18.9%. 1) Effective interest rate 20.6%. The total amount includes the calculated credit amount of SEK 1053 for Eiira Premium. Applies to 12 months of partial payment with Klarna. 2) Effective interest rate 20.5%. The total amount includes the calculated credit amount of SEK 558 for Eiira Premium. Valid for 6 months installment with Klarna. Credit provider and payee: Klarna Bank AB (publ) Sveavägen 46, 111 34 Stockholm. Amounts stated are an indication. Exact cost varies depending on the day of the month the purchase is made. For full terms and conditions, read more at klarna.com/en/terms.

Yes, it is easy. We will post a saliva collection kit and a return envelope to your home via Postnord. You simply spit saliva into the collection tube. If you need help, instructions are enclosed in the kit. Once you have collected saliva, you place the kit in the return envelope, which has a paid return label. You can then drop off the envelope at any Postnord service point.

The only other thing you need to do is to provide your details and our family’s medical history. The tools on our website will help you easily input the information. It is okay if you don’t provide your family medical history because you don’t know or you prefer not to.

The risk for 10 cancer types is mapped out by using the proven risk models and reference risk estimation data that are recommended in Swedish national guidelines. The below information is used as input to the mapping:

The results of your genetic tests. You can find more information in the section "What is the technology behind the genetic test?"
Your family medical history. Given the limitation of the current genomic science, your genetic test data alone cannot predict all risks. The family’s medical history contains much hereditary information. In some cases, family history alone can predict hereditary cancer risk. Therefore family medical history is used as part of the input.
Information on you and your medical history. Personal information such as ethnicity and ancestry roots have an impact on our hereditary risks. Your lifestyle and medical history affect the risk level.

Note that the risks we report are hereditary risks. That is the risk that you inherited from your biological parents.

The Eiira Premium test uses whole genome sequencing (WGS), the most advanced method that allows us to read and analyze the entire set of genetic information (DNA) in your genome, which consists of several billion base pairs. This vast amount of data can be used to identify variations or mutations in a person's DNA that may affect their health or make them more prone to certain diseases. The scale of the sequencing process and the need for specialized equipment, skilled technicians, and advanced computational tools make whole genome sequencing a more expensive option compared to other genetic testing methods, such as panel genetic tests commonly used by most testing providers and hospitals, or whole exome sequencing (WES) used in Eiira Classic.

WGS can be used to analyze both genomic and somatic DNA, but for Eiira's hereditary risk assessment it is performed on a person's genome. This enables the identification of genetic variations that may increase a person's risk of developing certain inherited diseases, such as breast cancer, colorectal cancer or other cancers and diseases, such as heart disease.

Eiira's test and the inclusion of 50 genes: The report includes 50 genes, based on Swedish guidelines, that are known to increase the risk of developing cancer. Genetic information is collected through whole genome sequencing (WGS) and analyzed with computational tools to find mutations linked to increased disease risk. The results are used to provide individualized recommendations for disease prevention, early detection and treatment, leading to more personalized care.

The advantage of staying up-to-date without taking another test: Using genome DNA for WGS has the advantage that it remains unchanged during a person's lifetime. This means that additional genetic tests for whole genome data are not needed. This allows for continuous updating with the latest genome research and cancer prevention measures without additional testing. Thanks to constant scientific progress, people can benefit from these breakthroughs without the hassle and expense of additional testing.

First of all, we need to understand that the risk is the likelihood of developing cancer:

Risk is not a diagnosis.
Some people with high risk never have cancer.
Similarly, people with low risk can still develop cancer.

Second, there are preventive measures to empower you. The report will inform you of proactive options available in Sweden. For many cancers, over 90% (close to 100% for breast cancers) survive if discovered early. The healthcare system has a number of monitoring programs to discover cancers early. We’ll inform you how to enter the Swedish healthcare system. There are also preventive healthcare partners that we can recommend to you.

Third, you can choose a one-hour free video meeting with one of our genetic counsellors who can address your questions and concerns and guide you through the process of understanding and taking preventive action.

Finally, if a pathogenic variant is found, it may be inherited by other family members. Therefore you may want to inform your siblings or children so that they have the option to discover and plan for themselves.

If you wish to discover more hereditary cancers, you can watch the recording of the talk given by Dr Svetlana from Karolinska Hospital at one of the Eiira events.

Genes associated

To make this assessment, we have analyzed 50 genes in your DNA to identify the possible presence of disease-causing variants that are linked to an increased cancer risk. These genes have been selected based on their association with certain specific cancers or cancer syndromes. The table below shows the genes linked to the 10 different cancers covered by the analysis (i.e. the genes where we know that people carrying a disease-causing variant have an increased risk of cancer).

Cancer type	Genes associated
Breast	BRCA1, BRCA2, PALB2, TP53, PTEN, CDH1, STK11, NF1, ATM, CHEK2, BARD1, RAD51C, RAD51D
Ovarian	BRCA1, BRCA2, PALB2, RAD51C, RAD51D, BRIP1, MLH1, MSH2, EPCAM, MSH6, PMS2
Colon	MLH1, MSH2, MSH6, PMS2, EPCAM, APC, MUTYH, STK11, SMAD4, BMPR1A, PTCH, PTEN, NTHL1, POLD1, POLE, MSH3, TP53
Prostate	BRCA2, HOXB13, BRCA1, MLH1, MSH2, MSH6, EPCAM, PMS2, ATM, CHEK2, PALB2, TP53
Melanoma	CDKN2A, BAP1, CDK4, POT1, TERT, MITF1, MC1R, ASIP, TYR, TYRP1, TP53
Kidney/Renal	VHL, FLCN, FH, MET, PTEN, SDHB, BAP1, SDHA, SDHC, SDHD
Thyroid	RET, APC, PTEN, DICER1, TP53
Uterine	MLH1, MSH2, MSH6, PMS2, PTEN
Pancreatic Cancer	BRCA1, BRCA2, ATM, PALB2, MLH1 , MSH2, EPCAM, MSH6, PMS2, STK11, CDKN2A
Hereditary diffuse gastric cancer	CDH1, CTNNA1

How it works

1. Collect saliva at home

We’ll post you a saliva collection kit right to your doorstep. Simply collect the saliva and return it to us using the provided prepaid envelope.

2. Tell us about you

With our web tool, you can enter your information, including details about your family if desired. These inputs will be used to map out your genetic risks.

3. Get your profile

Download your profile report. In the case of a high risk, you have the option to consult with a genetic counsellor for further guidance

4. Stay updated

You can choose to stay updated on the latest risk mapping and preventive measures resulting from new discoveries in genetic science.

Compare Eiira Classic and Premium

Features	Eiira Classic	Eiira Premium
Risk mapping for the ten most common cancers	✅	✅
Preventive measure for ten most common cancers	✅	✅
Updates for ten most common cancers	✅	✅
Future updates to cover other diseases	Limited	Unlimited
Lifetime updates of the latest discoveries in genetic science	Limited	Unlimited
Possibility to detect rare cancer variants	⭐⭐⭐⭐ (medium)	⭐⭐⭐⭐⭐ (most)
Genetic Sequencing Technology	Whole exome sequencing (WES)	Whole Genome Sequencing (WGS)
Choose your Eiira genetic test:	4990 kr	9990 kr